Reaction Friday: Formation of Acetals from Ketones

by James

in Aldehydes, Ketones, Organic Chemistry 2, Organic Reactions

Today’s video is about the formation of acetals from aldehydes and ketones, an important method for the protection of the carbonyl group.

One thing I forgot to mention in the video is that the reaction is an equilibrium – choosing alcohol as the solvent ensures that the equilibrium will be driven towards formation of the acetal, whereas treatment of acetals in aqueous acid leads to re-formation of the carbonyl group.

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{ 2 comments… read them below or add one }

Ricola February 27, 2012 at 10:19 am

Another great Reaction Friday post! Many many thanks and keep up the good work, it is highly appreciated!

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vivek kumar March 17, 2012 at 2:53 pm

very nice site where every concept in organic chemistry is cleared in easy way.
i am very happy to have access to this site

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