Reaction Map: Reactions of Organometallics

April 11, 2016

After the series of posts on Alcohols, I put together a large PDF that included the reactions of alcohols, alkenes, alkanes, alkynes, and alkyl halides on a large sheet. I was going to add our recent reactions of orga…

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New IUPAC Rules Make Molecular Names More Pronounceable, Friendlier

April 1, 2016

Bowing to pressure from consumer products companies facing a growing public relations nightmare over chemical ingredients in food, the International Union of Pure and Applied Chemistry (IUPAC) has made sweeping change…

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Liquid Gold: Pheromones In Doe Urine

Liquid Gold: Pheromones In Doe Urine

March 24, 2016

A few months ago my mom came down to visit, and we had a fun lunch at my favourite aquarium restaurant.  On our drive home, we got on the highway in the rain and turned a corner only to be confronted with a sea of …

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Our New Book, “Practice Organic Mechanisms”, Is Out

Our New Book, “Practice Organic Mechanisms”, Is Out

March 14, 2016

Today I’m delighted to announce a new book – Practice Organic Mechanisms, co-written with Dr. Michelle Sulikowski, Senior Lecturer of Organic Chemistry at Vanderbilt University. Practice Organic Mechanis…

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The Heck, Suzuki, and Olefin Metathesis Reactions (And Why They Don’t Belong In Most Introductory Organic Chemistry Courses)

The Heck, Suzuki, and Olefin Metathesis Reactions (And Why They Don’t Belong In Most Introductory Organic Chemistry Courses)

March 10, 2016

There has been a trend in recent years towards including transition metal catalyzed reactions in the introductory organic chemistry curriculum. The reactions most common covered are palladium catalyzed coupling react…

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Gilman Reagents (Organocuprates): What They’re Used For

Gilman Reagents (Organocuprates): What They’re Used For

February 5, 2016

Last time we talked about how to make Gilman reagents (organocuprates). In this post, we’ll talk about what they’re actually used for. Here’s a summary for today: So what are Gilman Reagents Used For…

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Gilman Reagents (Organocuprates): How They’re Made

Gilman Reagents (Organocuprates): How They’re Made

January 29, 2016

Here’s the summary for today’s post: Organometallics: What About The Rest Of The Periodic Table? In this whole series on organometallics so far has covered exactly TWO metals: lithium and magnesium (with a…

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Grignard Reactions And Synthesis (2)

Grignard Reactions And Synthesis (2)

January 19, 2016

Here’s the summary for today’s post on synthesis incorporating Grignard reagents and oxidants: Synthesis Using Grignard Reagents (Part 2) In the last post we saw how to approach some fairly straightforward…

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Synthesis Using Grignard Reagents (1)

Synthesis Using Grignard Reagents (1)

January 13, 2016

Here’s the bottom line for today’s post on solving synthesis problems involving Grignard reagents. Solving Synthesis Problems Involving Grignard Reagents Now that we’ve covered some of the most impor…

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Protecting Groups In Grignard Reactions

Protecting Groups In Grignard Reactions

December 16, 2015

Now that we’ve gone over the most useful reactions of Grignard reagents – addition to epoxides, aldehydes, ketones, and esters – let’s go back to the topic of how to make Grignard reagents, al…

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