Esters

Reactions of Grignard Reagents

Reactions of Grignard ReagentsDecember 10, 2015

Here’s the summary for today’s post: So far in this series we’ve introduced organometallic compounds and said that their carbons tend to be nucleophilic. We’ve learned how to make them from alk…

An Exercise In Mind Reading?

An Exercise In Mind Reading?April 8, 2013

The other day while going through Claisen condensations with a student, we came upon this pretty typical problem: The student duly deprotonated the alpha carbon of the ester to give the enolate, but stopped there. …

Weird Nomenclature In Carbonyl Chemistry

Weird Nomenclature In Carbonyl ChemistryMarch 26, 2012

Making it through the chemistry of carbonyl derivatives (ketones, aldehydes, carboxylic acids, esters, and more) there are at least two “weird” nomenclature issues that repeatedly come up to baffle student…

Reagent Friday – Diazomethane (CH2N2)

Reagent Friday – Diazomethane (CH2N2)November 5, 2011

In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday  I profile a different reagent that is commonly encountered in Org 1/ Org 2.  One of the things about learning organic chemist…

Reagent Friday: Di-isobutyl Aluminum Hydride (DIBAL)

Reagent Friday: Di-isobutyl Aluminum Hydride (DIBAL)August 26, 2011

In a blatant plug for the Reagent Guide, each Friday  I profile a different reagent that is commonly encountered in Org 1/ Org 2. Version 1.2 just got released, with a host of corrections and a new page index.  DIB…

Summary Sheet #8: The Oxidation Ladder

Summary Sheet #8: The Oxidation LadderAugust 15, 2011

Following up on this post, here’s an attempt at trying to put many of the reactions in organic chemistry in perspective, from the standpoint of oxidation state. Note that there’s a lot of gaps – very…

Oxidation Ladders

Oxidation LaddersAugust 8, 2011

Once you get a handle on oxidations and reductions, you might start to notice that with some molecules these reactions can proceed in sequences. For example, if you start with an alkane with a CH3 group, the alkane ca…

Oxidation and Reduction in Organic Chemistry

Oxidation and Reduction in Organic ChemistryAugust 1, 2011

Iron smelting!  Photo credit: http://sclowcountryoutdoors.blogspot.com/2011/02/iron-smelting-at-acba.html In the beginning, the term actually made sense. When the alchemists and medieval metallurgists started doing …

Reagent Friday: m-CPBA (meta-chloroperoxybenzoic acid)

Reagent Friday: m-CPBA (meta-chloroperoxybenzoic acid)June 17, 2011

The Organic Chemistry Reagent Guide is here!

The Organic Chemistry Reagent Guide is here!May 26, 2011

It’s taken a long time – late April through early May was hectic – but today I’m thrilled to finally announce the launch of the “Organic Chemistry Reagent Guide“, a guide designed e…