Synthesis

Grignard Reactions And Synthesis (2)

Grignard Reactions And Synthesis (2)January 19, 2016

Here’s the summary for today’s post on synthesis incorporating Grignard reagents and oxidants: Synthesis Using Grignard Reagents (Part 2) In the last post we saw how to approach some fairly straightforward…

Synthesis Using Grignard Reagents (1)

Synthesis Using Grignard Reagents (1)January 13, 2016

Here’s the bottom line for today’s post on solving synthesis problems involving Grignard reagents. Solving Synthesis Problems Involving Grignard Reagents Now that we’ve covered some of the most impor…

Synthesis (6) – Reactions of Alcohols

Synthesis (6) – Reactions of AlcoholsJuly 27, 2015

The Alcohol Reaction Map Having now finished (at long last) covering the key reactions of alcohols, let’s stop to put everything in perspective. Over the past 18 posts, we covered reactions such as: Ether format…

Williamson Ether Synthesis: Planning

Williamson Ether Synthesis: PlanningOctober 30, 2014

In the last post we introduced the Williamson ether synthesis,  one of the most straightforward ways we know of to make an ether. If you’ve been in the trenches long enough, you would have also noticed that it…

How Concepts Build Up In Org 2

How Concepts Build Up In Org 2September 9, 2014

OK. Having looked at the Org 1 Concept Map, let’s ask the next logical question: what does a typical Org 2 course look like? One general observation: the way functional groups are covered in your typical two-semeste…

Synthesis (5) – Reactions of Alkynes

Synthesis (5) – Reactions of AlkynesJanuary 29, 2014

Today, we’re going to add the reactions of alkynes to our reaction map, which will bring to a close all the major reactions we’ve discussed so far in a typical first semester course. Like alkenes, the main…

Synthesis (4) – Reactions of Alkenes

Synthesis (4) – Reactions of AlkenesJanuary 21, 2014

In the last post on alkenes we covered the reactions of alkyl halides and it made out tiny little reaction map explode into a cascade.  Here we’re really going to blow up our reaction map, because we’re g…

Synthesis (3) – Reactions of Alkyl Halides

Synthesis (3) – Reactions of Alkyl HalidesJanuary 10, 2014

In the last post, we began our discussion of synthesis by starting with the reactions of alkanes. Since we’ve learned only one important class of alkane reactions so far (free-radical halogenation), our “r…

Synthesis (2) – Reactions of Alkanes

Synthesis (2) – Reactions of AlkanesDecember 19, 2013

In this post we’re going to begin building our reaction map, starting with the simplest organic compounds of all: alkanes.*We’ve only learned one synthetically important class of alkane reaction: free-radi…

Introduction To Synthesis

Introduction To SynthesisDecember 17, 2013

By this point we’ve gone over all the major classes of reaction covered in many typical first semester organic chemistry courses.: acid base, substitution, elimination, addition, free-radical reactions, even oxi…