Conversion of acid chlorides to aldehydes using LiAlH(O-tBu)3

by James

Description: Addition of the bulky reducing agent lithium tri-t-butoxy aluminum hydride [LiAlH(O-tBu)3] to acid chlorides results in the formation of aldehydes.
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{ 2 comments… read them below or add one }

Stephanie B September 8, 2012 at 8:11 pm

Would it be possible to reverse this reaction and convert an aldehyde into an acid chloride?

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james September 12, 2012 at 4:30 pm

Not in one step, no. You’d need to oxidize it to a carboxylic acid and then convert it to the acid chloride. Those are two different steps.

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