Formation of Acetals from Aldehydes and Ketones

by James

Description: Ketones (or aldehydes) can be converted into acetals when treated with alcohols and acid. The byproduct is water. Content available for Reactionguide members only. Not a member? Get access for about 30 cents / day!

{ 3 comments… read them below or add one }

Brenda Greene February 27, 2012 at 3:58 pm

Thanks for this video!

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james February 28, 2012 at 9:03 pm

You’re very welcome, thanks Brenda.

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Anne March 21, 2012 at 2:22 am

Hi James!
Wow, sincere thanks for the video.
Just to clarify… You add a base to the reaction only when you need to deprotonate a H, like you did in Step 5. Otherwise, only the nucleophile will participate in addition reactions? Since protonating a ketone will make it more electrophilic, the strength of the nucleophile will not matter?

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