Formation of Grignard Reagents from Alkyl Halides

by James

Description: Treatment of alkyl halides with magnesium metal leads to formation of a Grignard reagent.
Content available for Reactionguide members only. Not a member? Get access for about 30 cents / day!

{ 1 comment… read it below or add one }

Polina Porotsky March 27, 2015 at 9:26 pm

Would I be correct in stating that the Grignard reagent is so basic, with such a high pKa (approx. 50) that it is able to de-protonate any hydrogen with a lower pKa? Additionally, that in a synthesis it will de-protonate the most acidic hydrogen?


Leave a Comment