What’s The Alpha Carbon In Carbonyl Compounds?
Alpha Carbon? Beta Carbon? Alpha, Beta Unsaturated Carbonyl? Making it through the chemistry of carbonyl derivatives (ketones, aldehydes, carboxylic acids, esters, and more) there are
Read moreAldehydes and Ketones
Nucleophilic Addition To Carbonyls
Nucleophilic Addition To Carbonyls The most important reaction of the carbonyl group (C=O) is the addition of nucleophiles to the carbonyl carbon, sometimes called, “1,2-addition”.
Read moreAldehydes and Ketones: 14 Reactions With The Same Mechanism
The Simple Two-Step Pattern For Seven Key Reactions Of Aldehydes And Ketones “There are just so many reactions! I can’t remember all the mechanisms!!” – distressed
Read moreSodium Borohydride (NaBH4) Reduction of Aldehydes and Ketones
Sodium borohydride (NaBH4) For the Reduction of Aldehydes and Ketones Sodium borohydride (NaBH4) is a convenient source of hydride ion (H-) for the reduction of
Read moreGrignard Reagents For Addition To Aldehydes and Ketones
Grignard Reagents: Their Formation, Reactions, And Reaction Mechanisms Today’s reagent is one that most students have experience in making at some point or another. Grignard
Read moreWittig Reaction
The Wittig Reaction: A Useful Method For Converting Aldehydes and Ketones To Alkenes Some time ago, we learned how to turn alkenes into carbonyls via
Read moreHydrates, Hemiacetals, and Acetals
Hydrates, Hemiacetals, and Acetals – Their Formation From Aldehydes/Ketones, And Mechanisms That Are As Easy As P-A-D-P-E-A-D Hydrates, hemiacetals and acetals are the products of
Read moreImines – Properties, Formation, Reactions, and Mechanisms
Imines – Their Properties, Formation, Reactions, and Mechanisms Imines are the nitrogen analogues of aldehydes and ketones, containing a C=N bond instead of a C=O
Read moreAll About Enamines
Enamines – formation, properties, reactions, and mechanisms. Enamines are formed from the reaction of a secondary amine with an aldehyde or ketone. Because they have
Read moreBreaking Down Carbonyl Reaction Mechanisms: Reactions of Anionic Nucleophiles (Part 2)
Continuing from Part 1, today I’ll cover the remaining 3 classes of mechanistic pathways for the reactions of anionic nucleophiles with carbonyl compounds, using the
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