Organic Chemistry 1

Hybrid Orbitals

Hybrid Orbitals

October 10, 2017

Summary of today’s discussion on hybrid orbitals! [Note: This post was co-authored with Matthew Pierce of Organic Chemistry Solutions.  Ask Matt about scheduling an online tutoring session here. ] In the las…

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How Do We Know Methane Is Tetrahedral?

How Do We Know Methane Is Tetrahedral?

August 25, 2017

In our review of atomic orbitals, we saw that the orbital configuration of the valence electrons of carbon is 2s22p2 as shown below:  Since the 2s orbital is lower in energy than 2p, it’s filled first. That mea…

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Review of Atomic Orbitals

Review of Atomic Orbitals

June 7, 2017

[Note: the following article is intended as a quick review on atomic orbitals for students enrolled in an introductory organic chemistry class who are assumed to have taken general chemistry. It is by no means a compl…

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Grignard Reactions And Synthesis (2)

Grignard Reactions And Synthesis (2)

January 19, 2016

Here’s the summary for today’s post on synthesis incorporating Grignard reagents and oxidants: Synthesis Using Grignard Reagents (Part 2) In the last post we saw how to approach some fairly straightforward…

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Organometallics Are Strong Bases

Organometallics Are Strong Bases

November 13, 2015

Last post we talked about how to make certain organometallics, specifically Grignard and organolithium reagents. One thing we saw is that it’s useful to think of them as “carbanions”, that is, carbon…

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Synthesis of Grignard and Organolithium Reagents

Synthesis of Grignard and Organolithium Reagents

November 9, 2015

In the last post we introduced the concept of organometallic compounds – molecules where carbon is bound to a less electronegative atom such as Li, Mg, Cu, and many other metals. We said that carbon in these mol…

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What’s An Organometallic?

What’s An Organometallic?

October 28, 2015

Quick summary for today – the first in a new series on organometallic compounds: Previously on MOC we’ve discussed how important dipoles are in determining the reactivity of a molecule. Wait: dipoles, yo…

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Thiols And Thioethers

Thiols And Thioethers

July 5, 2015

Here’s a summary of today’s post on thiols: Thiols and Thioethers One of the most powerful insights from learning the periodic table is the fact elements in the same period (column) have similar chemical …

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Protecting Groups For Alcohols

Protecting Groups For Alcohols

June 17, 2015

Summary for today’s post on Protecting Groups: When Alcohols Get In the Way As we’ve seen in previous posts in this series, alcohols are very versatile functional groups that participate in a variety of re…

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Intramolecular Reactions of Alcohols and Ethers

Intramolecular Reactions of Alcohols and Ethers

June 12, 2015

“Intramolecular Reactions Make Me Crumple Into The Fetal Position Crying For My Mommy” Here’s a topic which doesnt really fit neatly in with what we’ve discussed before but it’s essential to any …

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