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Home / Leaving group

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Leaving group

The departing group in a substitution or elimination reaction. Good leaving groups tend to be weak bases. Sometimes called a nucleofuge.

Related Articles:
  • Glossary: SN1
  • Glossary: MsCl
  • Nucleophilic Acyl Substitution (With Negatively Charged Nucleophiles)
  • Addition-Elimination Mechanisms With Neutral Nucleophiles (Including Acid Catalysis)
  • Acidic Hydrolysis of Amides
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