Now that we've gone through all the major reactions of alkynes, we can take a step back and look at the big picture. There are lots of reactions of alkynes. So what? you might ask. In this post I will try to convince you that alkynes are really useful building blocks for synthesizing a large variety … [Read more...]
Alkene Addition Pattern #3: The “Concerted” Pathway
In contrast to alkene addition reactions in the Carbocation Pathway and the 3-Membered Ring Pathway, we saw in the last two posts that hydroboration of alkenes is anomalous. The regioselectivity of the reaction is "anti-Markovnikov" and the stereochemistry of the addition is "syn": We also … [Read more...]