Master Organic Chemistry

Electrophilic Aromatic Substitution: Introduction

July 11, 2017 By James Ashenhurst 7 Comments

A key reaction of aromatic compounds is electrophilic aromatic substitution, where a C-H bond is broken and a new C-E bond (E being an electrophilic atom such as Cl, Br, N...) is formed. When we covered the reactions of alkenes a while back - a lot of reactions! -  we saw that the vast … [Read more...]

Filed Under: Aromaticity Tagged With: bromination, chlorination, electrophilic aromatic substitution, Friedel-Crafts, nitration, sulfonylation

Introduction To Aromaticity

January 20, 2017 By James Ashenhurst 5 Comments

In this post we introduce "aromaticity", a term for describing a collection of three [note] main properties that distinguish benzene from (hypothetical) cyclohexatriene. Extremely large resonance energy (36 kcal/mol) Delocalized electrons Undergoes substitution rather than addition … [Read more...]

Filed Under: Aromaticity Tagged With: aromaticity, benzene, electrophilic aromatic substitution, resonance energy, ring current, whup ass

Reaction Friday: Friedel Crafts Acylation

March 2, 2012 By James Ashenhurst 10 Comments

Today's Reaction Friday is about the Friedel Crafts acylation of benzene and other aromatics, an important example of electrophilic aromatic substitution. One thing I forgot to say at the bottom is that there's several different ways of showing how the acyl halide is activated by Lewis acid - … [Read more...]

Filed Under: Organic Chemistry 2, Organic Reactions Tagged With: acid halides, acyl halides, AlCl3, aromaticity, aromatics, benzene, electrophiles, electrophilic aromatic substitution, FeCl3, Friedel-Crafts, mechanisms, Reaction Friday

  • « Previous Page
  • 1
  • 2

Copyright © 2019 · MasterOrganicChemistry.com · All Rights Reserved
Organic Chemistry Is Awesome