[Advanced] Secondary Orbital Interactions - A Rationale For Why Endo Products Are Favored In The Diels-Alder Reaction In our last post, we noted that endo products tend to be favored over exo products in the Diels-Alder reaction. [We also introduced a quick-and-dirty rule for telling the … [Read more...]
Exo vs Endo Products In The Diels Alder: How To Tell Them Apart
Today we'll cover how to tell endo- and exo- products apart in the Diels-Alder reaction. Shortcut below. For the long winded walkthrough with lots of examples, read the post. Exo and Endo Products in the Diels-Alder In this series of articles on the Diels-Alder reaction, we've seen that: … [Read more...]
Stereochemistry of the Diels-Alder Reaction
Here's what we've learned about the Diels Alder reaction so far: [previous post in this series] 3 pi bonds are always broken 2 sigma bonds and a pi bond are always formed, resulting in a new six-membered ring electron withdrawing groups on the dienophile increase the reaction … [Read more...]