Intramolecular Friedel-Crafts Reactions
The Intramolecular Friedel-Crafts Reaction We explore the intramolecular Friedel-Crafts reaction in this post. But first, a very quick refresher on intramolecular reactions in general. Table
Read moreThe Intramolecular Friedel-Crafts Reaction We explore the intramolecular Friedel-Crafts reaction in this post. But first, a very quick refresher on intramolecular reactions in general. Table
Read moreHere’s the thing about the coverage of “amines” in Org 2: there’s no narrative. Unlike most chapters, it doesn’t start with a set of concepts
Read moreRearrangement Reactions: Substitution Reactions With Hydride Shifts In this post we cover several examples of reactions where carbocations form… but then a funny thing happens.
Read moreElimination Reactions (E1) That Occur With Rearrangements – Hydride Or Alkyl Shifts Where there are carbocations (see last post), rearrangement reactions are never far behind.
Read moreThe Pinacol Rearrangement The pinacol rearrangement is an acid-catalyzed rearrangement of 1,2-diols (vicinal diols) The acid serves to protonate one of the hydroxyl groups, which
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