socl2

PBr3 and SOCl2

PBr3 and SOCl2

March 20, 2015

Lately we’ve been talking a lot about converting alcohols to good leaving groups [halides] [tosylates and mesylates] You might think we’d be done already, but not yet! In today’s post we talk about a…

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Reaction Friday: Conversion of Alcohols to Alkyl Chlorides With SOCl2

Reaction Friday: Conversion of Alcohols to Alkyl Chlorides With SOCl2

March 10, 2012

Treatment of alcohols with thionyl chloride (SOCl2) converts alcohols to alkyl chlorides. When the reaction is performed on secondary alcohols with a stereocenter, the reaction proceeds with inversion of configuration…

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Reagent Friday: Thionyl Chloride (SOCl2)

Reagent Friday: Thionyl Chloride (SOCl2)

December 3, 2011

In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday  I profile a different reagent that is commonly encountered in Org 1/ Org 2.  If there’s one thing you learn how to do w…

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