Aldol Condensation

by James

Description: The aldol condensation is a reaction between an enolate (or enol) and an aldehyde or ketone that leads to the formation of a new carbon-carbon double bond. This is the product if an aldol addition reaction is heated for prolonged periods. The reaction is called a “condensation” because one molecule of water is formed from the two reactants.
Content available for Reactionguide members only. Not a member? Get access for about 30 cents / day!

 

{ 4 comments… read them below or add one }

David Carnevale March 6, 2014 at 3:11 am

Are there any conditions in which the ketone and alcohol remain and the double bond does not form in the final elimination step?

Reply

James May 26, 2014 at 4:00 pm

Yes – that’s “aldol addition”. Typically one avoids using heat in that process.

Reply

Petr Menzel May 26, 2014 at 3:09 am

Hi, is the “heat” always important? Or can I use another way for condensation? Thx, P.

Reply

James May 26, 2014 at 4:01 pm

Hi Petr – for aldol condensation, heat tends to favour elimination of water. If one wants to perform the aldol condensation, the best way to go about it is to heat the reaction mixture. To avoid the elimination, and to just perform an aldol addition reaction, typically one uses lower temperatures.

Reply

Leave a Comment