Formation of tosylates from alcohols

by James

Description: Treatment of alcohols with p-toluenesulfonyl chloride (TsCl) results in the formation of tosylates, which is an excellent leaving group.
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{ 4 comments… read them below or add one }

ratnadeep June 13, 2012 at 7:33 am

it’s excellent……..


Noman August 3, 2012 at 1:42 am

Excellent. I was reading Kaplan MCAT review and messed up with this reaction. This page gives clarity of thought that may be needed to do good on MCAT….


Simrandeep bahal May 15, 2013 at 12:48 pm

Is this reaction possible if Methyl group were not there on the benzene ring?


james May 16, 2013 at 12:37 pm

Yes, except it wouldn’t be tosylate, it benzenesulfonyl.


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