Formation of tosylates from alcohols

by James

Description: Treatment of alcohols with p-toluenesulfonyl chloride (TsCl) results in the formation of tosylates, which is an excellent leaving group.
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{ 4 comments… read them below or add one }

ratnadeep June 13, 2012 at 7:33 am

it’s excellent……..

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Noman August 3, 2012 at 1:42 am

Excellent. I was reading Kaplan MCAT review and messed up with this reaction. This page gives clarity of thought that may be needed to do good on MCAT….

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Simrandeep bahal May 15, 2013 at 12:48 pm

Is this reaction possible if Methyl group were not there on the benzene ring?

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james May 16, 2013 at 12:37 pm

Yes, except it wouldn’t be tosylate, it benzenesulfonyl.

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