Clemmensen Reduction of Ketones/Aldehydes to Alkanes

by James

Description: Addition of zinc amalgam, Zn(Hg) and acid to a ketone results in an alkane. This is called the Clemmensen reduction.
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Layla February 16, 2014 at 3:30 pm

On an Orgo 2 HW question we had to propose the synthesis of 1-bromo-3-propylbenzene. This was a multiple choice question, so we had to figure out the order of using the clemmensen reduction, bromination of arenes, and friedel crafts. What kept throwing me off was what order to put them in. It’s tricky! Could you explain how to approach that?

Thanks so much for your help, this is a great site and is extremely useful!


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