Reduction of esters to aldehydes using DIBAL

by James

Description: Esters can be reduced to aldehydes with diisobutylaluminum hydride (DIBAL), a bulky source of hydride ion. Content available for Reactionguide members only. Not a member? Get access for about 30 cents / day!

{ 5 comments… read them below or add one }

santosh kumar February 15, 2012 at 10:20 am

please tell me how 3 or 4 molecule of DIBAL are used to reduction of alkyl ester

give me detailed mechanism

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dong February 26, 2012 at 3:53 pm

what’s the meaning of Me on this diagram?

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james February 26, 2012 at 4:44 pm

Me means “methyl”, or CH3

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Esther July 6, 2013 at 12:50 pm

Hey, will lithium tri-tert-butoxyaluminum hydride work here, as well, or just for the acid halides? If not, why the selectivity?
Thanks in advance!

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james July 8, 2013 at 4:57 pm

Yep – it will also reduce aldehydes. That’s why it’s important to use only 1 equivalent when reducing acid halides, otherwise you get full reduction to the alcohol.

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