Reduction of esters to aldehydes using DIBAL
Description: Esters can be reduced to aldehydes with diisobutylaluminum hydride (DIBAL), a bulky source of hydride ion.
This page is available to MOC Members only.
Sign up here for about 30 cents/ day!
Description: Esters can be reduced to aldehydes with diisobutylaluminum hydride (DIBAL), a bulky source of hydride ion.
This page is available to MOC Members only.
Sign up here for about 30 cents/ day!
This site uses Akismet to reduce spam. Learn how your comment data is processed.
please tell me how 3 or 4 molecule of DIBAL are used to reduction of alkyl ester
give me detailed mechanism
what’s the meaning of Me on this diagram?
Me means “methyl”, or CH3
Hey, will lithium tri-tert-butoxyaluminum hydride work here, as well, or just for the acid halides? If not, why the selectivity?
Thanks in advance!
Yep – it will also reduce aldehydes. That’s why it’s important to use only 1 equivalent when reducing acid halides, otherwise you get full reduction to the alcohol.