Master Organic Chemistry Reaction Guide

Reduction of esters to aldehydes using DIBAL

Description: Esters can be reduced to aldehydes with diisobutylaluminum hydride (DIBAL), a bulky source of hydride ion.

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Comment section

5 thoughts on “Reduction of esters to aldehydes using DIBAL

  1. Hey, will lithium tri-tert-butoxyaluminum hydride work here, as well, or just for the acid halides? If not, why the selectivity?
    Thanks in advance!

    1. Yep – it will also reduce aldehydes. That’s why it’s important to use only 1 equivalent when reducing acid halides, otherwise you get full reduction to the alcohol.

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