Alkylation of enamines with alkyl halides
Description: Enamines are nucleophiles, and will react with alkyl halides to give alkylation products. Subsequent treatment with aqueous acid will give ketones.
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Org. Synth. 1961, 41, 76
DOI Link: 10.15227/orgsyn.041.0076
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4 thoughts on “Alkylation of enamines with alkyl halides”
tes: Acid can assist the reaction, making it faster in two ways. First, it makes the carbonyl more reactive for step 2, and it also allows for
？？where is the carbonyl?
Here, we’re talking about formation of the imine from the aldehyde or ketone.
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Glad you’re finding it useful Bruce.