Master Organic Chemistry Reaction Guide

Conversion of alcohols to alkyl chlorides using SOCl2

Description: Primary or secondary alcohols can be converted into alkyl chlorides through treatment with SOCl2.

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Real-Life Example:
Org. Synth. 1945, 25, 84
DOI Link: 10.15227/orgsyn.025.0084

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2 thoughts on “Conversion of alcohols to alkyl chlorides using SOCl2

    1. The purpose of the tertiary amine is to neutralize any HCl that is formed during the reaction. [Pyridine can also displace Cl from SOCl2 to give SOCl(pyr+) which has a better leaving group, but that’s a detail I didn’t want to go into].

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