Master Organic Chemistry Reaction Guide

Conversion of carboxylic acids into acid chlorides with SOCl2

Description: Thionyl chloride converts carboxylic acids into acid chlorides. The reaction liberates HCl and SO2 gas.

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Real-World Examples:

Org. Synth. 1929, 9, 32

DOI Link: 10.15227/orgsyn.009.0032

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Org. Synth. 1923, 3, 75

DOI Link: 10.15227/orgsyn.003.0075

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Org. Synth. 1930, 10, 88

DOI Link: 10.15227/orgsyn.010.0088

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Org. Synth. 1930, 10, 78

DOI Link: 10.15227/orgsyn.010.0078

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Org. Synth. 1949, 29, 33

DOI Link: 10.15227/orgsyn.029.0033

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Org. Synth. 1956, 36, 3

DOI Link: 10.15227/orgsyn.036.0003

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