Master Organic Chemistry Reaction Guide

Deprotonation of alkynes with base to give acetylide ions

Description: Treatment of an acetylene with a strong base such as NaNH2 results in acetylide ions
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1 thought on “Deprotonation of alkynes with base to give acetylide ions

  1. I’ve got an exam question problem: So I’ve added n-BuLi to an alkyne, from this a suspect I product lithium acetylide, however the question asks for ANOTHER reagent in the reaction, could it be LiH4-, to get rid of the lithium or is there something im missing?

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