Formation of Acetals from Aldehydes and Ketones
Description: Ketones (or aldehydes) can be converted into acetals when treated with alcohols and acid. The byproduct is water.
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Real-Life Examples:
Org. Synth. 1926, 6, 64
DOI Link: 10.15227/orgsyn.006.0064
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Org. Synth. 1962, 42, 1
DOI Link: 10.15227/orgsyn.042.0001
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Thanks for this video!
You’re very welcome, thanks Brenda.
Hi James!
Wow, sincere thanks for the video.
Just to clarify… You add a base to the reaction only when you need to deprotonate a H, like you did in Step 5. Otherwise, only the nucleophile will participate in addition reactions? Since protonating a ketone will make it more electrophilic, the strength of the nucleophile will not matter?