Master Organic Chemistry Reaction Guide

Formation of enamines from ketones/aldehydes and secondary amines

Description: When ketones are treated with secondary amines and heated with an acid catalyst, a condensation reaction occurs, resulting in loss of H2O and formation of an enamine.

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Real-Life Examples:

Org. Synth. 1968, 48, 56

DOI Link: 10.15227/orgsyn.048.0056

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Org. Synth. 1961, 41, 65

DOI Link: 10.15227/orgsyn.041.0065

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