Master Organic Chemistry Reaction Guide

Oxidation of aldehydes to carboxylic acids using Cr(VI)

Description: Chromium trioxide (CrO3) and water will oxidize aldehydes to carboxylic acids.

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Real-World Examples:

Org. Synth. 1936, 16, 39

DOI Link: 10.15227/orgsyn.016.0039

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Org. Synth. 1930, 10, 82

DOI Link: 10.15227/orgsyn.010.0082

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Comment section

4 thoughts on “Oxidation of aldehydes to carboxylic acids using Cr(VI)

  1. Thanks for all of the reactions! Your website is extremely helpful. Shouldn’t the reagent in example 3 say: K2Cr2O7?
    Thanks again!

  2. so i understand you can use bases for the last step to deprotonate the compound in the last step, but why do you have h2so4 in one of the examples? this would protonate right?

    1. The purpose of H2SO4 is to protonate potassium dichromate, K2Cr2O7 to give chromic acid H2CrO4 which is the active oxidizing agent. Usually you’ll just see H+ but I wanted to be more specific. It’s not related to the last step. Water is a good enough base to do the elimination to give the carbonyl.

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