Master Organic Chemistry Reaction Guide

Reductive Amination

Description: Aldehydes and ketones can be converted into amines, through formation of an imine and treatment with a reducing agent. This is called “reductive amination”.

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Real-Life Examples:

Org. Synth. 1943, 23, 68

DOI Link: 10.15227/orgsyn.023.0068

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Org. Synth. 1950, 30, 59

DOI Link: 10.15227/orgsyn.030.0059

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strong>Org. Synth. 1972, 52, 124

DOI Link: 10.15227/orgsyn.052.0124

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Comment section

2 thoughts on “Reductive Amination

  1. The finished product in the mechanism you are showing has an additional carbon that it should not have. To the right of the red H in the finished product should be an additional hydrogen.

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