Master Organic Chemistry

Leaving Groups Are Nucleophiles Acting In Reverse

June 25, 2012 By James Ashenhurst 5 Comments

We've covered "what makes a good leaving group" before - the weaker the base, the better the leaving group. In this short post, I just want to make an observation. Note how similar nucleophiles are to leaving groups: A nucleophile donates a pair of electrons A leaving group accepts a pair of … [Read more...]

Filed Under: Alkyl Halides, Organic Chemistry 1, Understanding Electron Flow Tagged With: basicity, conjugate base, equilibrium, finkelstein, leaving groups, nucleophiles, substitution reactions

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