Introducing the Reaction Guide
My main goal at Master Organic Chemistry has always been to provide students with useful resources that they can’t easily find anywhere else. About six
Read moreReaction Friday
Reaction Friday: Keto-Enol Tautomerism
Today’s Reaction Friday is all about keto-enol tautomersm, the chemistry equivalent of Jekyll and Hyde. Included: Tautomers are constitutional isomers (not resonance forms) The same
Read moreReaction Friday – Fischer Esterification
The Fischer esterification is one of the most important reactions of carboxylic acids. Treatment of carboxylic acids with an alcohol in the presence of acid
Read moreReaction Friday – Reduction of Alkynes to Alkenes with Na/NH3
My apologies for the interruption. I seem to have wrested control of my blog back from the cats for now, but I’m not sure how
Read moreReaction Friday: Conversion of Alcohols to Alkyl Chlorides With SOCl2
Treatment of alcohols with thionyl chloride (SOCl2) converts alcohols to alkyl chlorides. When the reaction is performed on secondary alcohols with a stereocenter, the reaction
Read moreReaction Friday: Friedel Crafts Acylation
Today’s Reaction Friday is about the Friedel Crafts acylation of benzene and other aromatics, an important example of electrophilic aromatic substitution. One thing I forgot
Read moreReaction Friday: Formation of Acetals from Ketones
Today’s video is about the formation of acetals from aldehydes and ketones, an important method for the protection of the carbonyl group. One thing I
Read moreReaction Friday: Addition of Grignard Reagents to Ketones
Grignard reagents are very useful carbon-based nucleophiles and will readily form carbon-carbon bonds with carbonyl compounds. Here the reaction of Grignard reagents with ketones is
Read moreReaction Friday: Oxymercuration of Alkenes using Hg(OAc)2 and NaBH4
Reaction Friday is back!!! Today’s video is on a commonly encountered reaction for making alcohols, the oxymercuration of alkenes using Hg(OAc)2 and water, followed by
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