Formation of imines from primary amines and ketones

by James

Description: Reaction of a primary amine with an aldehyde or ketone results in an imine. The reaction results in the formation of one equivalent of water.
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{ 3 comments… read them below or add one }

sreekanth September 27, 2012 at 8:45 am

why primary amines under diazonium reaction

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james September 30, 2012 at 9:13 am

If you use secondary amines you can’t form the triple bond.

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Seah November 2, 2013 at 1:15 pm

For the first step, why does e proton source attack the carbonyl oxygen instead of the more basic amine in the reaction mixture? Is it because of resonance in e protonated carbonyl?

Do we add e acid and e amine at the same time?

Can the acid be a weak acid as strong acidic conditions may protonate e amine and render it non nucleophilic?

Thanks :)

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