Friedel-Crafts acylation of aromatic groups to give ketones

by James

Description: In the presence of a catalyst such as FeCl3 or AlCl3 , acyl chlorides will add to aromatic groups to form aromatic ketones. This is called the Friedel-Crafts acylation reaction.
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{ 4 comments… read them below or add one }

Kahla Vise

Hi there! I’m doing a problem in my book (don’t worry, it’s not graded hw), and I was wondering, would it be possible to add an anhydride with this reaction? Or would sterics/other reasons prevent that?

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Amelia Abbott-Frey

Can friedel-Crafts acylation be used to create an aldehyde. In other words, can the R group on the chloride acyl be a H?

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Kartik Anand

Thats Gatterman Koch Reaction. It is based on F.C. Acylation

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Caitlin Aschliman

My textbook uses aluminum as the metal ion and you used iron (III). Does it matter what metal ion you use so long as the halide matches?

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