Friedel-Crafts acylation of aromatic groups to give ketones

by James

Description: In the presence of a catalyst such as FeCl3 or AlCl3 , acyl chlorides will add to aromatic groups to form aromatic ketones. This is called the Friedel-Crafts acylation reaction.
Content available for Reactionguide members only. Not a member? Get access for about 30 cents / day!

{ 2 comments… read them below or add one }

Kahla Vise April 6, 2014 at 6:25 pm

Hi there! I’m doing a problem in my book (don’t worry, it’s not graded hw), and I was wondering, would it be possible to add an anhydride with this reaction? Or would sterics/other reasons prevent that?

Reply

Amelia Abbott-Frey October 8, 2014 at 10:51 am

Can friedel-Crafts acylation be used to create an aldehyde. In other words, can the R group on the chloride acyl be a H?

Reply

Leave a Comment