Master Organic Chemistry Reaction Guide

SN2 of Cyanide with Alkyl Halides to give Nitriles

Description: Alkyl halides (or tosylates) will react with cyanide ion to give alkyl cyanides (nitriles) in an SN2 reaction. 

This page is available to MOC Members only.
Sign up here for about 30 cents/ day!


Real-Life Examples:

Org. Synth. 1922, 2, 9
DOI link: 10.15227/orgsyn.002.0009

Click to Flip

Org. Synth. 1928, 8, 52
DOI link: 10.15227/orgsyn.008.0052

Click to Flip

Org. Synth. 1925, 5, 103
DOI link: 10.15227/orgsyn.005.0103

Click to Flip

Org. Synth. 1936, 16, 35
DOI link: 10.15227/orgsyn.016.0035

Click to Flip

Org. Synth. 1938, 18, 50
DOI link: 10.15227/orgsyn.018.0050

Click to Flip

Org. Synth. 1943, 23, 33
DOI link: 10.15227/orgsyn.023.0033

Click to Flip

Comments

Comment section

4 thoughts on “SN2 of Cyanide with Alkyl Halides to give Nitriles

  1. Hi,

    The first example reaction is for acetal formation…not alkyl halides for nitriles. Other than that, this is fantastic! Finally understand reactions properly! :)

Leave a Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.