zaitsev

Bulky Bases in Elimination Reactions

Bulky Bases in Elimination Reactions

October 24, 2012

We’ve recently talked about Zaitsev’s rule in elimination reactions, and how the transition state leading to the more substituted alkene is lower in energy. The bottom line in elimination reactions is that…

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Walkthrough of Elimination Reactions (1)

Walkthrough of Elimination Reactions (1)

August 28, 2012

As you’ve probably noticed by now, organic chemistry is a lot different from physics. Why do I say that? Because when we’re looking to predict what reaction might occur in a given situation, we don’t…

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Reagent Friday: Potassium t-butoxide [KOC(CH3)3]

Reagent Friday: Potassium t-butoxide [KOC(CH3)3]

October 29, 2011

In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday  I profile a different reagent that is commonly encountered in Org 1/ Org 2.  Sometime back in general chemistry you (hopefull…

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Introduction to Elimination Reactions

Introduction to Elimination Reactions

October 10, 2011

As  part 4 of the most important reactions you learn in org 1, (acid-base, substitution, and addition) here’s an introduction to the elimination reaction. This series requires that you understand how to read li…

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The Most Annoying Exceptions in Org 1 (Part 2)

The Most Annoying Exceptions in Org 1 (Part 2)

February 4, 2011

Last time we talked about how some interesting electronic effects can lead to unexpected results in organic chemistry. Today we look at three examples of how steric factors can  lead to unexpected products (or lack o…

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