Elimination Reactions (1): Introduction And The Key Pattern
Introduction to Elimination Reactions As you’ve probably noticed by now, organic chemistry is a lot different from physics. When we’re looking to predict what reaction
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Elimination Reactions (2): The Zaitsev Rule
Elimination Reactions: The Zaitsev Rule Elimination reactions usually occur such that they are removing a hydrogen from the carbon attached to the fewest hydrogens. This
Read moreElimination Reactions Are Favored By Heat
Elimination Reactions Are Favored By Heat Elimination reactions are often in competition with substitution reactions Generally speaking, adding heat tends to increase the proportion of elimination products relative
Read moreTwo Elimination Reaction Patterns
A Tale of Two Elimination Reaction Patterns Like I said in the introduction to substitution reactions, organic chemistry is an empirical, experimental science. We make
Read moreThe E1 Reaction
The E1 Reaction – Three Key Pieces of Evidence, and a Mechanism Last time in this walkthrough on elimination reactions, we talked about two types
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E2 Mechanism – How The E2 (Elimination, Biomolecular) Reaction Works Having gone through the E1 mechanism for elimination reactions, we’ve accounted for one way in
Read moreE1 vs E2: Comparing the E1 and E2 Reactions
E1 versus E2 : Comparing The E1 and E2 Reactions Now that we’ve gone through the mechanisms of the E1 and E2 reactions, let’s take
Read moreAntiperiplanar Relationships: The E2 Reaction and Cyclohexane Rings
Antiperiplanar Relationships Between C-H And The Leaving Group: The E2 Reaction and Cyclohexane Rings Here we come to a very testable application of the E2 reaction
Read moreBulky Bases in Elimination Reactions
Elimination Reactions Using “Bulky Bases” – When The Zaitsev Product Is Minor We’ve recently talked about Zaitsev’s rule in elimination reactions, and how the transition
Read moreComparing the E1 vs SN1 Reactions
The Important Role of The Counter-Ion In Determining E1 vs SN1 E1 will generally be favored over SN1 when heat is applied Secondly, in E1
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