Master Organic Chemistry Reaction Guide

SN2 reaction of organocuprates (Gilman reagents) with alkyl halides to give alkanes

Description: Alkyl halides (or tosylates) will react with organocuprates (Gilman reagents) to form alkanes in an SN2 reaction

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3 thoughts on “SN2 reaction of organocuprates (Gilman reagents) with alkyl halides to give alkanes

  1. Hi, please for explaining how is created bond C1 and C2 in Mechanism? C1 is (+) and Cu is (-) —> C2 is (+) I suppose. Thx. P.

  2. That is correct. C-2 attached to Cu is nucleophilic (partially negative) and C1 attached to Br is electrophilic (partially positive).

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