Reactions of Enols – Aldol Condensation, Halogenation, Mannich Reaction In a previous post on keto-enol tautomerism, we described the keto and enol forms. In this
Read moreHere’s another great example of how one reagent used in a certain context performs one thing, and in a different context performs a completely different
Read moreHydration of Alkenes to Give Alcohols When alkenes are treated with aqueous acid (H3O+) they can be converted to alcohols. Formation of the new C-OH
Read moreHydrates, Hemiacetals, and Acetals – Their Formation From Aldehydes/Ketones, And Mechanisms That Are As Easy As P-A-D-P-E-A-D Hydrates, hemiacetals and acetals are the products of
Read moreLithium Diisopropyl Amide (LDA), A Strong, Sterically Hindered Base In a blatant plug for the Reagent Guide, each Friday I profile a different reagent that is
Read moreSodium Amide (Sodamide, NaNH2), A Strong Base For The Deprotonation Of Terminal Alkynes (Among Other Uses) In a blatant plug for the Reagent Guide, each Friday
Read moreChemical Equilibria In chemistry, irreversible reactions get all the press: the familiar fires and explosions that are well represented on YouTube. The thing is, not
Read moreProtonation and Deprotonation: How They Affect Reactivity One thing has been missing from our discussion of acid-base reactions. Who cares? What does it matter that
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