ortho para meta

Aromatic Synthesis (3) – Sulfonyl Blocking Groups

Aromatic Synthesis (3) – Sulfonyl Blocking Groups

November 26, 2018

I Just Want The ORTHO- Product, Thank You Question: Just how selective are ortho- para, directors for the ortho- and para- products, respectively? There are two ortho positions and one para. All else being equ…

Read the full article →
More Reactions on the Aromatic Sidechain: Reduction of Nitro Groups and the Baeyer Villiger

More Reactions on the Aromatic Sidechain: Reduction of Nitro Groups and the Baeyer Villiger

October 8, 2018

Quick summary of this post on three new reactions of aromatic substituents: reduction of nitro groups to amines, protection of amines as amides, and on the Baeyer-Villiger reaction of ketones: Three More Reactions Of …

Read the full article →

Ortho-, Para- and Meta- Directors in Electrophilic Aromatic Substitution

January 29, 2018

Two Important Reaction Patterns: Ortho- , Para- and Meta- Directors It’s one thing to learn about electrophilic aromatic substitution reactions of benzene itself. But once you move beyond benzene, that’s w…

Read the full article →
Electrophilic Aromatic Substitution – The Mechanism

Electrophilic Aromatic Substitution – The Mechanism

November 9, 2017

Last post in this series on reactions of aromatic groups we introduced activating and deactivating groups in Electrophilic Aromatic Substitution (EAS). We learned that electron-donating substituents on the aromatic ri…

Read the full article →