Structure Determination Case Study: Deer Tarsal Gland Pheromone

Structure Determination Case Study: Deer Tarsal Gland PheromoneAugust 23, 2016

In January 1969, the Beatles released their “Yellow Submarine” single and performed their last live gig, Richard Nixon was inaugurated as president, and Brownlee et. al. published their seminal paper, …

Natural Product Isolation (2) – Purification of Crude Mixtures Overview

Natural Product Isolation (2) – Purification of Crude Mixtures OverviewAugust 12, 2016

  Previously,  we showed a few examples of preparing crude extracts from plants and other organisms. While sometimes (rarely) we get lucky and obtain an extract that is predominantly one compound, a more repre…

Natural Product Isolation (1) – Extraction

July 12, 2016

“Let’s plant catnip”, they said. “It will keep away mosquitoes”, they said. [from r/pics . h/t @curiouswavefn] In the previous post on some notable molecules from nature, we saw many ex…

Now Available – The Spectroscopy Pack (PDF)

July 7, 2016

One of the most common complaints I hear from readers of Master Organic Chemistry is that there isn’t a lot of coverage of spectroscopy. And I’ve been sorry to say, they’re right. Spectroscopy prob…

A Gallery of Some Interesting Molecules From Nature

April 21, 2016

[In which we inch our way, very very slowly, towards spectroscopy and structure determination] Recently I wrote about my experience of finding a bottle of  “White Tail Doe Urine” in the back of my rental …

Reaction Map: Reactions of Organometallics

April 11, 2016

After the series of posts on Alcohols, I put together a large PDF that included the reactions of alcohols, alkenes, alkanes, alkynes, and alkyl halides on a large sheet. I was going to add our recent reactions of orga…

New IUPAC Rules Make Molecular Names More Pronounceable, Friendlier

April 1, 2016

Bowing to pressure from consumer products companies facing a growing public relations nightmare over chemical ingredients in food, the International Union of Pure and Applied Chemistry (IUPAC) has made sweeping change…

Liquid Gold: Pheromones In Doe Urine

Liquid Gold: Pheromones In Doe UrineMarch 24, 2016

A few months ago my mom came down to visit, and we had a fun lunch at my favourite aquarium restaurant.  On our drive home, we got on the highway in the rain and turned a corner only to be confronted with a sea of …

Our New Book, “Practice Organic Mechanisms”, Is Out

Our New Book, “Practice Organic Mechanisms”, Is OutMarch 14, 2016

Today I’m delighted to announce a new book – Practice Organic Mechanisms, co-written with Dr. Michelle Sulikowski, Senior Lecturer of Organic Chemistry at Vanderbilt University. Practice Organic Mechanis…

The Heck, Suzuki, and Olefin Metathesis Reactions (And Why They Don’t Belong In Most Introductory Organic Chemistry Courses)

The Heck, Suzuki, and Olefin Metathesis Reactions (And Why They Don’t Belong In Most Introductory Organic Chemistry Courses)March 10, 2016

There has been a trend in recent years towards including transition metal catalyzed reactions in the introductory organic chemistry curriculum. The reactions most common covered are palladium catalyzed coupling react…