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Reaction Guide Updates
Last updated: April 30th, 2026 |
Seventeen new pages have been recently added to the Reaction Guide:
- Olefin Metathesis
- The Strecker Synthesis
- Birch Reduction
- Cope Rearrangement
- Claisen Rearrangement
- Addition of Organolithiums to Aldehydes/Ketones
- Addition of Organolithiums to Carboxylic Acids
- Halogenation of Enols
- Conversion of Esters to Amides
- Acidic Hydrolysis of Amides
- Reduction of Amides to Amines
- Protection and Deprotection of Amines
- Electrocyclic Reactions
- 1,2- and 1,4- Additions To Dienes
- Cope Elimination
In addition, over the past year or so, all Reaction Guide pages have been updated with completely new images that incorporate additional examples, redrawn mechanisms, and fixed typos. Hundreds of references to key papers from the literature have also been added.
Thanks to everyone who has been a MOC member this past year, thanks to all those who wrote in with suggestions and brought attention to typos and other necessary corrections, and thanks to Nick and Arjun for helping with the schemes and references.
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