Ace Your Next Organic Chemistry
Exam.

With the MOC Membership

Join Here

SN2

The Gabriel Synthesis

The Gabriel Synthesis For Making Primary Amines We’ve seen previously that it’s hard to *usefully* build amines through the SN2 reaction, because once amines start

Read more

Some Reactions of Azides

Azide Ion: Structure, Properties, and Substitution Reactions Table of Contents The Azide Ion Is A Great Nucleophile Organic Azides As “Masked” Amines Exploding On The

Read more

The Williamson Ether Synthesis

The Williamson Ether Synthesis In the Williamson Ether Synthesis, an alkyl halide (or sulfonate, such as a tosylate or mesylate) undergoes nucleophilic substitution (SN2) by an alkoxide to give an ether.

Read more

Epoxide Ring Opening With Base

Ring-opening of epoxides with basic nucleophiles Epoxides are cyclic ethers with considerable ring strain (about 13 kcal/mol) Epoxides undergo reaction with nucleophiles under basic conditions

Read more