LiAlH[Ot-Bu]3 For The Reduction of Acid Halides To Aldehydes
Reduction of Acid Halides To Aldehydes With LiAlH(OtBu)3 or Rosenmund’s Catalyst Acid halides can be reduced to aldehydes through use of the bulky reducing agent
Read moreReagent Friday: Potassium tert-butoxide [KOC(CH3)3]
Potassium tert-Butoxide (KOt-Bu) Is A Bulky Base In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday I profile a different reagent that
Read moreGuest post: “I went from being afraid of tests to actually looking forward to them”.
I love getting letters from people about their experiences with organic chemistry. I love it even more when they share some of the techniques and
Read moreAlkene Reactions: Ozonolysis
Ozonolysis of Alkenes and Alkynes Alkenes can undergo oxidative cleavage with ozone (O3) to give carbonyl compounds, cleaving the C=C bond The reaction generates an ozonide intermediate,
Read more“Compare Organic Chemistry To A Movie…”
Love this quote, from Organic Chemistry 1 as a Second Language by David R. Klein (fuller review to come) on organic chemistry and memorization. You
Read moreThe SN1, E1, and Alkene Addition Reactions All Pass Through A Carbocation Intermediate
The Carbocation Intermediate That Connects The SN1, E1, And Alkene Addition Reactions Was going to include this in my last post but it was getting
Read moreWittig Reaction
The Wittig Reaction: A Useful Method For Converting Aldehydes and Ketones To Alkenes Some time ago, we learned how to turn alkenes into carbonyls via
Read more7 Factors that stabilize negative charge in organic chemistry
Understanding The 7 Key Factors That Stabilize Negative Charge (And Ultimately, Basicity) Like I wrote about in a previous post, (See article: Curved Arrows For
Read moreReagent Friday: Sodium (Na)
Sodium Metal (Na) As A Reagent In Organic Chemistry In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday I profile a different
Read more7 Factors That Stabilize Positive Charge in Organic Chemistry
Stabilization Of Positive Charge In Organic Chemistry: 7 Key Factors Just to clarify: make sure you’re familiar with how formal charge can mislead before you
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