epoxides

Reactions of Grignard Reagents

Reactions of Grignard Reagents

December 10, 2015

Here’s the summary for today’s post: So far in this series we’ve introduced organometallic compounds and said that their carbons tend to be nucleophilic. We’ve learned how to make them from alk…

Read the full article →
Opening Of Epoxide With Base

Opening Of Epoxide With Base

February 10, 2015

Opening of epoxides with base a summary of what we talk about today: In the last post we discussed the reactions of epoxides under acidic conditions and saw how they resembled the “3-membered ring” family of alken…

Read the full article →
Opening of Epoxides With Acid

Opening of Epoxides With Acid

February 2, 2015

Here’s what we’re covering in this post. Opening Epoxides With Aqueous Acid In the last post, we saw some examples of how epoxides are considerably more reactive towards breakage than are ordinary ethers. …

Read the full article →
Reagent Friday: Grignard Reagents

Reagent Friday: Grignard Reagents

October 14, 2011

In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday  I profile a different reagent that is commonly encountered in Org 1/ Org 2.  NOTE – I said that the Reagents app would…

Read the full article →
Reagent Friday: m-CPBA (meta-chloroperoxybenzoic acid)

Reagent Friday: m-CPBA (meta-chloroperoxybenzoic acid)

June 17, 2011
Read the full article →
The Most Annoying Exceptions in Org 1 (Part 2)

The Most Annoying Exceptions in Org 1 (Part 2)

February 4, 2011

Last time we talked about how some interesting electronic effects can lead to unexpected results in organic chemistry. Today we look at three examples of how steric factors can  lead to unexpected products (or lack o…

Read the full article →