Addition Reactions of Alkenes In previous series, we’ve discussed acid-base reactions, nucleophilic substitution reactions, and elimination reactions. These represent three of the four most important
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The Second-Most Important Mechanism In Carbonyl Chemistry – Carbonyl Elimination The reverse of nucleophilic addition to the C=O bond (giving a tetrahedral intermediate) is elimination
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Introduction to Rearrangement Reactions Reactions that involve a carbocation intermediate may be accompanied by rearrangements where a pair of electrons from a C-H or C-C bond
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Identifying Carbons Where Substitution and Elimination Reactions Can Take Place Substitution and elimination reactions need a leaving group in order for them to occur. Look
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Reactions of Enols – Aldol Condensation, Halogenation, Mannich Reaction In a previous post on keto-enol tautomerism, we described the keto and enol forms. In this
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The Role of The Substrate In Substitution & Elimination Reaction: SN2 vs E1/SN1 Deciding whether a reaction is SN1/SN2/E1/E2 first of all requires understanding the
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Introduction to Elimination Reactions As you’ve probably noticed by now, organic chemistry is a lot different from physics. When we’re looking to predict what reaction
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Proton Transfer All acid-base reactions are technically proton transfers, where a bond to H+ breaks, and a bond to H+ forms. However, the term “proton
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The Hofmann Elimination Of Alkylammonium Salts: Examples and Mechanism The Hofmann Elimination is an elimination reaction of alkylammonium salts that forms C-C double bonds [pi
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Cope Elimination The “Cope Elimination” is a reaction where an amine is oxidized to an intermediate called an “N-oxide“, which, when heated, acts as the
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