A Fourth Alkene Addition Pattern – Free Radical Addition
Free Radical Addition Of HBr To Alkenes With ROOR (Peroxides) We’ve seen that there are three major alkene reactivity patterns [carbocation, three membered ring, and
Read moreResonance Structures Should Have Full Octets (If Possible!)
Resonance Structures With Positive Charge: Four Key Principles The most important resonance form is generally the one where the charges are minimized. However, sometimes you
Read moreIntramolecular Reactions of Alcohols and Ethers
The Intramolecular Reactions Here’s a topic which doesn’t really fit neatly in with what we’ve discussed before but it’s essential to any discussion of alcohols
Read moreResonance Structures: Negative Charges Are Best Placed On The Least Basic Atom
Evaluating Resonance Structures With Negative Charges: Some Key Principles So far in discussing resonance forms we’ve mentioned three important principles that govern which resonance form
Read moreHidden Hydrogens, Hidden Lone Pairs, Hidden Counterions
Hidden Hydrogens, Lone Pairs, and Counter-Ions Time is precious. Drawing the full structures of chemical formulae out takes time. Shaving an extra 10-20 seconds here
Read moreLiAlH[Ot-Bu]3 For The Reduction of Acid Halides To Aldehydes
Reduction of Acid Halides To Aldehydes With LiAlH(OtBu)3 or Rosenmund’s Catalyst Acid halides can be reduced to aldehydes through use of the bulky reducing agent
Read moreReagent Friday: Potassium tert-butoxide [KOC(CH3)3]
Potassium tert-Butoxide (KOt-Bu) Is A Bulky Base In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday I profile a different reagent that
Read moreGuest post: “I went from being afraid of tests to actually looking forward to them”.
I love getting letters from people about their experiences with organic chemistry. I love it even more when they share some of the techniques and
Read moreAlkene Reactions: Ozonolysis
Ozonolysis of Alkenes and Alkynes Alkenes can undergo oxidative cleavage with ozone (O3) to give carbonyl compounds, cleaving the C=C bond The reaction generates an ozonide intermediate,
Read more“Compare Organic Chemistry To A Movie…”
Love this quote, from Organic Chemistry 1 as a Second Language by David R. Klein (fuller review to come) on organic chemistry and memorization. You
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