alkyl halides

Gilman Reagents (Organocuprates): How They’re Made

Gilman Reagents (Organocuprates): How They’re Made

January 29, 2016

Here’s the summary for today’s post: Organometallics: What About The Rest Of The Periodic Table? In this whole series on organometallics so far has covered exactly TWO metals: lithium and magnesium (with a…

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Making Alkyl Halides From Alcohols

Making Alkyl Halides From Alcohols

February 27, 2015

Making Alkyl Halides From Alcohols In today’s post we show that treating alcohols with HCl, HBr, or HI (which all fall under the catch-all term “HX” where X is a halide) results in the formation of a…

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Synthesis (5) – Reactions of Alkynes

Synthesis (5) – Reactions of Alkynes

January 29, 2014

Today, we’re going to add the reactions of alkynes to our reaction map, which will bring to a close all the major reactions we’ve discussed so far in a typical first semester course. Like alkenes, the main…

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Synthesis (3) – Reactions of Alkyl Halides

Synthesis (3) – Reactions of Alkyl Halides

January 10, 2014

In the last post, we began our discussion of synthesis by starting with the reactions of alkanes. Since we’ve learned only one important class of alkane reactions so far (free-radical halogenation), our “r…

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Synthesis (2) – Reactions of Alkanes

Synthesis (2) – Reactions of Alkanes

December 19, 2013

In this post we’re going to begin building our reaction map, starting with the simplest organic compounds of all: alkanes.*We’ve only learned one synthetically important class of alkane reaction: free-radi…

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Markovnikov’s Rule (1)

Markovnikov’s Rule (1)

February 8, 2013

Onward with addition reactions! Quiz time: let’s see if you can recognize the patterns in the following 3 reactions. Look carefully. What do each of the major products have in common? Hopefully you can see that …

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The E1 Reaction

The E1 Reaction

September 19, 2012

Last time in this walkthrough on elimination reactions, we talked about two types of elimination reactions. In this post, we’re going to dig a little bit deeper on one type of elimination reaction, and based on…

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Elimination Reactions (2): Zaitsev’s Rule

Elimination Reactions (2): Zaitsev’s Rule

August 31, 2012

So far, we’ve only looked at some very simple elimination reactions. In this post we’ll look at some examples where we start to see some of the extra “wrinkles” that can be present in eliminati…

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Reagent Friday: Thionyl Chloride (SOCl2)

Reagent Friday: Thionyl Chloride (SOCl2)

December 3, 2011

In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday  I profile a different reagent that is commonly encountered in Org 1/ Org 2.  If there’s one thing you learn how to do w…

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Introduction to Free Radical Substitution Reactions

Introduction to Free Radical Substitution Reactions

October 25, 2011

The four posts on acid-base, substitution, addition, and elimination covered the 4 main reactions in organic chemistry I. In this second series of posts we go beyond these to introduce a few of the less common (…

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