Rearrangement Reactions (1) – Hydride Shifts
For nucleophilic substitution, the pattern of bonds that form and break is pretty straightforward. You break C-(leaving group) and you form C-(nucleophile). A straight swap. But
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Introduction to Nucleophilic Substitution Reactions
Following up on the 4 most important patters of reactions in Org 1, and introduction to acid-base reactions, here’s the second major pattern. It’s called
Read moreThe 4 Major Classes of Reactions in Org 1
At least 80% of the reactions you will learn in Org 1 fall into one of these 4 categories. The sooner you can get into the habit of recognizing bond formation and breakage the better off you will be.
Read moreWhat makes a good leaving group?
A leaving group is a nucleophile acting in reverse; it accepts a lone pair as the bond between it and its neighbor (usually carbon for
Read moreSteric Hindrance is Like a Fat Goalie
Sportswriter Todd Gallagher asked a question that every hockey fan has probably asked at one point. “Could a morbidly obese goaltender succeed in the NHL?”
Read moreThe SN2 Mechanism
Having gone through the two different types of substitution reactions, and talked about nucleophiles and electrophiles, we’re finally in a position to reveal the mechanism
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