The Diels-Alder Reaction
The Diels-Alder Reaction Is Awesome Today we’ll introduce a reaction I consider to be the most useful and powerful reaction in all of organic chemistry: the
Read moreThe Diels-Alder Reaction Is Awesome Today we’ll introduce a reaction I consider to be the most useful and powerful reaction in all of organic chemistry: the
Read moreCyclic Dienes (e.g. Cyclopentadiene) and Cyclic Dienophiles In The Diels-Alder Reaction Last post in this series we introduced the Diels-Alder reaction. We saw that no
Read moreStereochemistry of the Diels-Alder Reaction The Diels-Alder reaction always has the same pattern of bonds that form and break. Three pi bonds are broken, and
Read moreToday we’ll cover how to tell endo– and exo- products apart in the Diels-Alder reaction. Shortcut below. For the long-winded walkthrough with lots of examples, read more below. Table
Read moreThe HOMO and LUMO In The Diels Alder Reaction The Diels-Alder reaction is a concerted reaction between a diene (with 4 pi-electrons) and a dienophile
Read more[Advanced] Secondary Orbital Interactions – A Rationale For Why Endo Products Are Favored In The Diels-Alder Reaction In our last post, we noted that endo products tend to be
Read moreKinetic and Thermodynamic Control In The Diels-Alder Reaction: The Diels Alder Reaction Is Reversible At High Temperatures We’ve seen that the products of addition to
Read moreMechanism and Examples of the Retro Diels-Alder Reaction In the last post in this series on the Diels-Alder [See: Diels-Alder Reaction: Kinetic and Thermodynamic Control]
Read moreThe Intramolecular Diels-Alder Reaction Is Awesome Exam preparation tip: Instructors often include questions on intramolecular versions of familiar reactions on exams, since they involve no
Read moreRegiochemistry (“Regioselectivity”) In The Diels-Alder Reaction The Diels-Alder is an onion, and we just keep peeling back the layers. When non-symmetrical dienes react with non-symmetrical
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