alcohols

Synthesis (6) – Reactions of Alcohols

Synthesis (6) – Reactions of Alcohols

July 27, 2015

The Alcohol Reaction Map Having now finished (at long last) covering the key reactions of alcohols, let’s stop to put everything in perspective. Over the past 18 posts, we covered reactions such as: Ether format…

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Protecting Groups For Alcohols

Protecting Groups For Alcohols

June 17, 2015

Summary for today’s post on Protecting Groups: When Alcohols Get In the Way As we’ve seen in previous posts in this series, alcohols are very versatile functional groups that participate in a variety of re…

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Alcohol Oxidation: “Strong” and “Weak” Oxidants

Alcohol Oxidation: “Strong” and “Weak” Oxidants

May 6, 2015

Here’s what we’ll talk about today: reagents for the oxidation of alcohols! Oxidations Of Alcohols With “Eye Of Newt”, “Wing of Bat”, and “Powdered Unicorn Horn” Here we…

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Elimination Reactions of Alcohols

Elimination Reactions of Alcohols

April 16, 2015

Here’s a summary of what we talk about in today’s post. Hydrohalic acids (HX)  plus alcohols give substitution products… We just saw that treating an alcohol with a strong hydrohalic acid – th…

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PBr3 and SOCl2

PBr3 and SOCl2

March 20, 2015

Lately we’ve been talking a lot about converting alcohols to good leaving groups [halides] [tosylates and mesylates] You might think we’d be done already, but not yet! In today’s post we talk about a…

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Making Alkyl Halides From Alcohols

Making Alkyl Halides From Alcohols

February 27, 2015

Making Alkyl Halides From Alcohols In today’s post we show that treating alcohols with HCl, HBr, or HI (which all fall under the catch-all term “HX” where X is a halide) results in the formation of a…

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Opening Of Epoxide With Base

Opening Of Epoxide With Base

February 10, 2015

Opening of epoxides with base a summary of what we talk about today: In the last post we discussed the reactions of epoxides under acidic conditions and saw how they resembled the “3-membered ring” family of alken…

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Cleavage Of Ethers With Acid

Cleavage Of Ethers With Acid

November 19, 2014

I’ve been looking forward to today’s post for a long time! We’ve gone through so many different ways of synthesizing ethers, and finally we get to talk about all the exciting things we get to do with…

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Ether Synthesis Via Alcohols And Acid

Ether Synthesis Via Alcohols And Acid

November 14, 2014

Last post I got a little ahead of myself. I was all excited about getting into the reactions of ethers, and forgot that there’s one last method for ether synthesis that we haven’t covered. It’s actua…

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Alcohols (3) – Acidity and Basicity

Alcohols (3) – Acidity and Basicity

October 17, 2014

In the last post we said that one of the keys to the reactions of alcohols as we go forward is that the conjugate acid is a better leaving group and the conjugate base is a better nucleophile. We might have gotten a …

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