The Second-Most Important Mechanism In Carbonyl Chemistry – Carbonyl Elimination The reverse of nucleophilic addition to the C=O bond (giving a tetrahedral intermediate) is elimination
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Proton Transfer All acid-base reactions are technically proton transfers, where a bond to H+ breaks, and a bond to H+ forms. However, the term “proton
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The Simple Two-Step Pattern For Seven Key Reactions Of Aldehydes And Ketones “There are just so many reactions! I can’t remember all the mechanisms!!” – distressed
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Today I’m delighted to announce a new book – Practice Organic Mechanisms, co-written with Dr. Michelle Sulikowski, Senior Lecturer of Organic Chemistry at Vanderbilt University. Practice Organic
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Halogenation of Alkynes With Cl2, Br2, and I2 Like alkenes, alkynes can undergo halogenation with Cl2, Br2, or I2. When 1 equivalent of the halogen
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Alkyne Reaction Mechanisms That Pass Through A “Concerted” Pathway – Cyclopropanation, Hydrogenation, Hydroboration Various reactions that proceed through a concerted mechanism such as hydrogenation, hydroboration,
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Bromination, Chlorination, and Halohydrin Formation from Alkenes Alkenes undergo halogenation when treated with Cl2, Br2 and (less commonly) I2 to give vicinal dihalides These reactions
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How Do The Electrons Move? “Electron Pushing” With The Three Types Of Curved Arrows When learning any new reaction, I think you always have to
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Curved Arrows In Organic Chemistry: Always Change Two (And Only Two!) Charges Here’s a handy little trick for accounting for charges when you draw curved
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Hydrates, Hemiacetals, and Acetals – Their Formation From Aldehydes/Ketones, And Mechanisms That Are As Easy As P-A-D-P-E-A-D Hydrates, hemiacetals and acetals are the products of
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